Scientific achievements
- We have developed an experimental flow for synthetic gene design, allowing for direct cloning and eukaryote expression of very short peptides. This method was employed for the direct expression of PreImplantationFactorTM, owned by and in collaboration with BioIncept LLC (NJ, USA).
- We have developed a method and also a diagnostic kit for the detection of natively folded protein products encoded by fusion genes like TMPRSS2:ERG with prognostic significance in prostate cancer. Patent pending. Application filed in National Patent Office, 2014.
- We have developed a method combining high resolution confocal microscopy with 3D image processing and analysis, and Principal Component Analysis to identify the effects of specific innate immunity ligands (LPS, ie-DAP) on downstream interaction between autophagy marker LC3 and inflammasome molecule NALP3. Published in Nat Sci Rep, 2016.
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