IBIR-BAS projects 2008-2012
IBIR-BAS projects 2008-2012
Projects with additional financing from programs supported by EU, NATO, UNESCO a\and other international organizations
| Title of the research theme, leader | Funding |
| 1.ReProForce FP-7- REGPOT-2009-1 reinforcement of the research capacity of the bulgarian institute “biology and immunology of reproduction”. | 2009-2013, 1499181 euro |
| 2. COST Action FA0602 ” Bioactive Food Components, Mitochondrial Function and Health”
Prof. D.Kacheva Assoc. prof. E.Kistanova |
2007-2011
20 000 euro – participation in the meetings, organization of the meeting in Sofia, short-term scientific mobility |
| 3. COST Action F1201 ” Epigenetics and Periconception Environment – Periconception environment as an epigenomic lever for optimising food production and health in livestock”
Prof. D.Kacheva Assoc. prof. E.Kistanova |
2012-2016
till now 700 euro – participation in the meeting |
| 4. NEAT , Network to enhance the use of economics in animal health education, research and policy making in Europe and beyond. LLP-1 -2012-1 UK-ERAZMUS- ENM; LLP Programme (Lifelong learning
GA-2012-3830/001-001 Assoc. prof. B.Georgiev |
2012-2015
till now 2700 euro |
| The role of matrix metalloproteinases 2 and 9 and ADAMS phamily in pathophysiology of breast cancer in humnas.
Assistant Prof. Rumen Kirilov Dimitrov, Assoc. Prof. P. Rashev Prof. Hans Donat
|
2011-2013
10 000 euro for consumables and travel |
Regional projects, e.g. South Eastern Europe (SEE) and non- European. Bilateral agreements between academies of sciences. These projects are on the base of equivalent without money exchange between Academies of Sciences
| Expression of genes and proteins with a role in reproduction – biomarkers for infringements.
PI from IBIR: Associate Professor Dr. Margarita Mollova with the Institute of Genetics, Czech Academy of Sciences |
2007-2010
accommodation support, no funding for research activities |
| Proteomics of seminal plasma from ram, boar and dog in relation to cryotolerance of spermatozoa of these species.
PI form IBIR, Associate Professor Dr. Maria Ivanova-Kicheva with the Univ. off Warmia and Mazury, Poland |
2007-2010
accommodation support, no funding for research activities |
| Expression of genes and proteins with a role in reproduction – biomarkers for infringements.
PI from IBIR: Assistant Professor Julieta Dineva with the Institute of Genetics, Czech Academy of Sciences |
2011-2013
accommodation support, no funding for research activities |
| In vitro maturation and fertilization of pig oocytes and cultivation of early embryos until blastocyst cleavage
PI form IBIR, Professor D. Kacheva with the Instute of Animal Physiology and Genetics, Czech Republic |
2011-2013
accommodation support, no funding for research activities |
| Improvement of embryo transfer biotechnology in domestic animals.
PI form IBIR, Professor D. Kacheva Egyptian Academy of Sciences |
2009-2012
accommodation support, no funding for research activities |
20.1. National projects
Projects financed by the Ministry of Education and Science
| Localization and function of stress proteins in testicular germ cells in heat-induced and spontaneous apoptosis.
Associate Professor Dr. Margarita Mollova |
2007-2010
25000 lv |
| New temperature-sensitive superoxide dismutase from Antarctic fungi: biotechnological study, chemical characterization and application”. Associate Professor Dr. Margarita Mollova | 2010-2012
19530 lv
|
| The Importance of calcium-binding protein Secretagogin in hormone-secreting neuroendocrine cells.
Assistant Professor Teodora Daneva |
2007-2010
20600 lv |
| Building Scientific Research Centre on the problems in reproductive health” under Program “Development of scientific infrastructure”. Associate Professor Dr. Margarita Mollova | 2008-2012
800 000 lv |
| Isolation and Characterization of Human Skin Stem Cells: a search for new targets for the therapy of skin cancer.
Prof. I. Kehayov |
2008-2012
250 000 lv |
| Investigation on the plasticity of human mesenchymal stem cells.
Prof. S. Kyurkchiev |
2007-2010
29 200 lv |
| Investigation on the possibilities for control of proliferation of tumor cells through specific siRNA mollecules.
Prof. I. Kehayov |
2007-2010
25 000 lv |
| Investigation on antioxidant potential of melatonin for improving the reproductive capacity in idiopathic male infertility and varicocele.
Assoc. Prof. R. Konakchieva |
2008-2010
20 000 lv |
| Comparative studies on methods for isolation, culturing, differentiation and cryopreservation of hematopoietic stem cells from umbilical blood.
Assoc. Prof. P. Todorov |
2009-2012
100 000 lv |
| Investigation of approaches for higher effect of buffalo reproduction.
Assoc. Prof. M. Ivanova-Kicheva, Prof. D. Kacheva |
2007-2011
25 000 lv |
| Co-financing project to the ReProForce FP-7- REGPOT-2009-1 reinforcement of the research capacity of the bulgarian institute “biology and immunology of reproduction”.
Project Coordinator Prof. M. Mollova |
2009-2013
324 030 lv |
| Gene regulatory networks based on siRNA, transcription factors and fusion oncoproteins in prostate cancerogenesis and their application in diagnostics and therapeutics
Assistant Professor Dr Krassimira Todorova-Hayrabedyan |
2011-2013
44976 lv |
| Ananlysis of rare Bulgarian sheep breeds – preservation and sustained utilisation
Assist. Prof. Aleksander Kukov |
2011-2013
46445 lv |
| “Manual on reproduction in domestic animals and reproductive biotechnologies”
Assoc. Prof. M. Sabev
|
2011-2012
4956 lv |
| Izolation, characterization and in vitro differentiation of ovarian stem cells
Assoc. Prof. P.Todorov
|
2012-
150 000 lv |
Projects financed by Bulgarian Academy of Sciences (salary only) 2010-2012
Total financial input for salary 2010-2012 – 700529 lv/ 358174 euro
| Title | Duration |
| Development of xeno-free conditions for culturing of human embryonic stem cells (line BG01V).
Assoc. Prof. Tsvetelina Oreshkova |
2010-2012 |
| Development of laboratory protocols for derivation of induced pluripotent stem cells.
Assoc. Prof. Milena Mourdjeva
|
2010-2012 |
| Influence of the biological active substances on the female reproductive potential and embryo development.
Assoc. Prof. Е.Kistanova
|
2007-2012 |
| Morphological characteristic of sperm and spermatozoid-specific proteins and enzymes, related to fertilizing ability.
Assoc. Prof. B.Georgiev
|
2007-2012 |
| Immuno-endocrine regulation of luteinisation and apoptosis in preovulatory folicle.
Assistant Professor Ivaylo Vangelov, Assistant Professor Julieta Dineva
|
2010-2012 |
| Non-invasive test of the genetic potential of cumulus cells as biomarkers for selecting oocytes in program for in vitro fertilization.
Assistant Professor Dr Krassimira Todorova-Hayrabedyan
|
2010-2012 |
| Pregnancy and Diabetes.
Dr Katya Todorova, Ph.D. and assistant Kameliya Petkova
|
2008-2010 |
| Studies over cytotoxicity on PC3 cell line of porfirin compounds.
Assistant Professor Diana Zasheva
|
2010-2012 |
| Influence of antiphospholipids antibody on reproductive cells.
Assistant Professor K. Uzunova
|
2008-2010 |
| Investigation of viability of Ovis aries spermatozoa after seminal plasma separation.
Assoc. Prof. M. Sabev
|
2008-2010 |
| Studying the effect of different protectors and biotechnologies for storage of mammal’s spermatozoa at low temperatures.
Assoc. Prof. M Ivanova-Kicheva and Assistant K. Lazov
|
2008-2010 |
| Investigation of sheep fertility after artificial insemination with semen stored at low temperatures.
Assistant Prof. R. Stefanov
|
2008-2010 |
| Characterization of the protective role of seminal plasma proteins on the biological characteristics and adaptation capabilities of ram spermatozoa stored at low temperatures.
Assoc. Prof. M Ivanova-Kicheva
|
2010-2012 |
| Investigation of the role of metaloproteinases in mamary gland development in dogs
Associate Professor Pavel Rashev
|
2011-2012 |
| SCGN as probable tumor supressive gene
Assistant Professor Teodora Daneva
|
2011-2012 |
| Investigation of relation between sensor signals and reproductive processes in normal and pathological conditions
Prof. S. Lolov
|
2011-2012 |
| Influence of egg yolk lipoproteins on boar spermatosoids in low temperature
Assoc. Prof. M Ivanova-Kicheva
|
2009-2011 |
| Strutural analysis of small proteins isolated from ram seminal plasma
Assoc. Prof. M Ivanova-Kicheva
|
2011-2012 |
| Investigation of oxidative-antioxidative status, qualitative parameters of spermatozoa and some biochemical characteristics in boar seminal fluid.
Assistant Prof. R. Stefanov
|
2011-2012 |
| Damage on untracellular proteins as a result of toxic effect of free radicals in cryopreserved ram sperm
Assistant Prof. R. Stefanov A
|
2011-2012 |
| Role of neuroendocrine factors in ethiology of methabolic and endocrine resistence
Ass. Prof Georgi Georgiev
|
2011-2012 |
| Investigation of melatonon action in seminal fluid in healthy men and patients with idiopatic infertility
Assoc. Prof. R. Konakchieva
|
2011-2012 |
| Sanitary aspects of embriobiotechnology in animals
Prof. D. Kacheva
|
2010-2012 |
| Optimization of biotechnology for cryoconservation of bufalo sperm
Assoc. Prof. M Ivanova-Kicheva
|
2012- |
| Involvement of metalloproteinases in spermatogenesis and fertilization in humans
Associate Professor Pavel Rashev
|
2012- |
| Studies on mucous immunity and the immune response
Prof. S. Lolov |
2012- |
| Staged specific expression of a DNA helicase RUVBL1/TIP49a during spermatogenesis
Assistant Professor Teodora Daneva |
2012- |
| Molecular interactions between human mesenchymal stem cells and tumors – a model to search for new antitumor agents
Medical University, Sofia – prof. I.Altynkova; IBIR team is presented by Assoc. Prof. Milena Mourdjeva
|
2011- |
| Expression of immunoregulatory markers in in vitro decidualization of human stromal cells isolated from a parietal deciduas
Assoc. Prof. Tsvetelina Oreshkova
|
2012- |
| Biochemical characterization of endometriosis peritoneal fluid
Assoc. Prof. Maria Stamenova
|
2012- |
| System for regulation of the output of mitosis and its importance for the development of prostate cancer
Assistant Professor Diana Zasheva
|
2012- |
| Optimization of systems of selection and reproduction in sheep from SPBM for efficient production. Analysis and evaluation of genealogical structure
Prof. D. Kacheva for IBIR and Prof. E. Raycheva for Kostinbrod
|
2012- |
| Validation of the biological effects of H. rhodopensis to genotoxic and oxidative stress and activation of innate immunity
Assistant Professor Dr SorenHayrabedyan
|
2012- |
Projects with additional financing fromGovernmental institutions and Bulgarian companies
| Project “Impact of anti-ovarian antibodies on fertility”.
Assistant Professor Julieta Dineva , Assistant Prof. Ivaylo Vangelov
|
2010-2012
300 lv |
| Supporting the practice of AI of sheep
Assoc. Prof. M. Sabev, two participants |
2010-2012
150 lv
|
| Cooperative program for research and development with Obst.
Gyn. Center “Dimitrov” Res. Assoc. P. Todorov
|
2010-2012
consumables only |
| The role of metalloproteinases in pathogenesis of breast cancer and their significance as prognostic markers for early diagnosis of disease.
Assistant Prof. Rumen Kirilov Dimitrov
|
2010
consumables only |
| Development of modern biotechnology in the cryopreservation of semen from different livestock species.
Assoc. Prof. M. Ivanova-Kicheva,
|
2010-2012
11000 lv |